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New labdane diterpenoids from Croton laui and their anti-inflammatory activities.
- Source :
-
Bioorganic & Medicinal Chemistry Letters . Oct2016, Vol. 26 Issue 19, p4687-4691. 5p. - Publication Year :
- 2016
-
Abstract
- Nine new labdane diterpenoids ( 1 – 9 ) were isolated from the aerial parts of Croton laui , along with eight known analogues ( 10 – 17 ). Their structures were identified on the basis of the spectral data (IR, UV, HRESIMS, 1D and 2D NMR), and the structure of 8 was confirmed by single crystal X-ray diffraction analyses. In addition, compounds 1 , 4 , 7 , 8 , and 14 showed weak anti-inflammatory activities in LPS-stimulated RAW 264.7 cells. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0960894X
- Volume :
- 26
- Issue :
- 19
- Database :
- Academic Search Index
- Journal :
- Bioorganic & Medicinal Chemistry Letters
- Publication Type :
- Academic Journal
- Accession number :
- 117915626
- Full Text :
- https://doi.org/10.1016/j.bmcl.2016.08.052