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Pediatric Miller Fisher Syndrome Complicating an Epstein-Barr Virus Infection.

Authors :
Communal, Céline
Filleron, Anne
Baron-Joly, Sandrine
Salet, Randa
Tran, Tu-Anh
Source :
Pediatric Neurology. Oct2016, Vol. 63, p73-75. 3p.
Publication Year :
2016

Abstract

<bold>Background: </bold>Miller Fisher syndrome, a variant of Guillain-Barré syndrome, is an acute inflammatory demyelinating polyradiculoneuropathy that may occur weeks after a bacterial or viral infection. Campylobacter jejuni and Haemophilus influenzae are frequently reported etiological agents.<bold>Patient Description: </bold>We describe a boy with Miller Fisher syndrome following Epstein-002DBarr virus primary infectious mononucleosis. He presented with bilateral dysfunction of several cranial nerves and hyporeflexia of the limbs but without ataxia. Miller Fisher syndrome was confirmed by the presence of anti-GQ1b antibodies in a blood sample. Epstein-Barr virus was identified by polymerase chain reaction and serology.<bold>Conclusion: </bold>Epstein-Barr virus should be considered as a Miller Fisher syndrome's causative agent. The physiopathology of this condition may involve cross-reactive T-cells against Epstein-Barr virus antigens and gangliosides. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
08878994
Volume :
63
Database :
Academic Search Index
Journal :
Pediatric Neurology
Publication Type :
Academic Journal
Accession number :
118077276
Full Text :
https://doi.org/10.1016/j.pediatrneurol.2016.06.018