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Simple synthesis of silver nanoparticles functionalized cuprous oxide nanowires nanocomposites and its application in electrochemical immunosensor.
- Source :
-
Sensors & Actuators B: Chemical . Nov2016, Vol. 236, p241-248. 8p. - Publication Year :
- 2016
-
Abstract
- In this work, silver nanoparticles functionalized cuprous oxide nanowires (Ag@Cu 2 O) nanocomposites were synthesized by a simple method. The nanostructure of it could be well confirmed by a scanning electron microscope (SEM) image. Due to the good synergistic effect between silver nanoparticles (Ag NPs) and cuprous oxide nanowires (Cu 2 O NWs), Ag@Cu 2 O nanocomposites displayed a good electrocatalytic performance towards the reduction of hydrogen peroxide (H 2 O 2 ). Cyclic voltammograms (CVs) were employed to investigate electrocatalytic mechanism of it. Using Ag@Cu 2 O nanocomposites as the labels, a novel and ultrasensitive sandwich-type electrochemical immunosensor was developed for the quantitative detection of carcinoembryonic antigen (CEA). Due to the special electrochemical performance of Ag@Cu 2 O nanocomposites, the facile and sensitive fabrication of the designed immunosensor was achieved. Under optimal conditions, the designed immunosensor exhibited a wide linear range with a low detection limit. It also displayed an electrochemical performance with good reproducibility, selectivity and stability, which would provide potential applications in the clinical diagnosis of other tumor markers. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09254005
- Volume :
- 236
- Database :
- Academic Search Index
- Journal :
- Sensors & Actuators B: Chemical
- Publication Type :
- Academic Journal
- Accession number :
- 118152036
- Full Text :
- https://doi.org/10.1016/j.snb.2016.06.021