Classical Kaposi sarcoma: case reports with unusual presentation on the penis and scrotum.

Background Kaposi sarcoma (KS) is the most common vascular neoplasm. Any skin area could be involved, including the genitalia. Traditionally, classic KS lesions have a general distribution, often involving skin of the feet and legs, and to a lesser extent, that of the hands, arms, and trunk. KS limited to the external genitalia is extremely rare in HIV seronegative individuals. Methods We report six patients of classic KS with generalized dermal KS lesions. Results Two of them presenting with unusual KS lesions on the penis and scrotum beside the other dermal lesions. Patients were HIV negative and human herpes virus eight positive. Histological examination showed classical KS. Conclusions Primary KS of the penis and scrotum is rare but could occur in HIV-negative patients. [ABSTRACT FROM AUTHOR]