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Assessing the intracellular fate of rhodium(ii) complexes.

Authors :
Minus, Matthew B.
Kang, Marci K.
Knudsen, Sarah E.
Liu, Wei
Krueger, Michael J.
Smith, Morgen L.
Redell, Michele S.
Ball, Zachary T.
Source :
Chemical Communications. 10/7/2016, Vol. 52 Issue 78, p11685-11688. 4p.
Publication Year :
2016

Abstract

Rhodium(ii)–fluorophore conjugates have strong rhodium-based fluorescence quenching that can be harnessed to report on a conjugate's cellular uptake and the intracellular decomposition rate. Information gleened from this study allowed the design of an improved STAT3 metalloinhibitor. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
52
Issue :
78
Database :
Academic Search Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
118287939
Full Text :
https://doi.org/10.1039/c6cc05192h