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Left Atrial Enlargement on Transthoracic Echocardiography Predicts Left Atrial Thrombus on Transesophageal Echocardiography in Ischemic Stroke Patients.
- Source :
-
BioMed Research International . 10/16/2016, Vol. 2016, p1-6. 6p. - Publication Year :
- 2016
-
Abstract
- Background. Transesophageal echocardiogram (TEE) is superior to transthoracic echocardiogram (TTE) in detecting left atrial thrombus (LAT), a risk factor for stroke, but is costly and invasive, carrying a higher risk for complications. Aims. To determine the utility of using left atrial enlargement (LAE) on TTE to predict LAT on TEE. Methods. AIS patients who presented in 06/2008–7/2013 and underwent both TTE and TEE were identified from our prospective stroke registry. Analysis consisted of multivariate logistic regression with propensity score adjustment and receiver operating characteristic (ROC) area under the curve (AUC) analyses. Results. 219 AIS patients underwent both TTE and TEE. LAE on TTE was detected in 113 (51.6%) of AIS patients. Patients with LAE on TTE had higher proportion of LAT on TEE (8.4% versus 1.0%, p=0.018). LAE on TTE predicted increased odds of LAT on TEE (OR=8.83, 95% CI 1.04–74.83, p=0.046). The sensitivity and specificity for LAT on TEE by LAE on TEE were 88.89% and 52.20%, respectively (AUC=0.7054, 95% CI 0.5906–0.8202). Conclusions. LAE on TTE can predict LAT detected on TEE in nearly 90% of patients. This demonstrates the utility of LAE on TTE as a potential screening tool for LAT, potentially limiting unneeded costs and complications associated with TEE. [ABSTRACT FROM AUTHOR]
- Subjects :
- *THROMBOSIS diagnosis
*CHI-squared test
*CONFIDENCE intervals
*ECHOCARDIOGRAPHY
*FISHER exact test
*ISCHEMIA
*PROBABILITY theory
*STROKE
*TRANSESOPHAGEAL echocardiography
*MULTIPLE regression analysis
*RETROSPECTIVE studies
*RECEIVER operating characteristic curves
*DESCRIPTIVE statistics
*LEFT heart atrium
*ODDS ratio
*MANN Whitney U Test
*DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 23146133
- Volume :
- 2016
- Database :
- Academic Search Index
- Journal :
- BioMed Research International
- Publication Type :
- Academic Journal
- Accession number :
- 118823542
- Full Text :
- https://doi.org/10.1155/2016/7194676