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Negative HPV testing among patients with biopsy-proven cervical intraepithelial neoplasia grade 2/3 or cervical cancer.
- Source :
-
International Journal of Gynecology & Obstetrics . Feb2017, Vol. 136 Issue 2, p229-231. 4p. - Publication Year :
- 2017
-
Abstract
- <bold>Objective: </bold>To determine the proportion of patients diagnosed with cervical cancer or cervical intraepithelial neoplasia grade 2 or 3 (CIN 2/3) despite testing negative for HPV.<bold>Methods: </bold>A prospective study was conducted at a university hospital in Barcelona, Spain, between March 2003 and January 2015 among women with abnormal cytology results according to the Bethesda classification system. All participants underwent HPV testing, cytology, and colposcopy.<bold>Results: </bold>Among 1376 participants, 609 (44.3%) were diagnosed with CIN 2/3. Of these women, 74 (12.2%) tested negative for HPV. Among 479 women with colposcopy-guided biopsy sampling showing CIN 2/3, cone biopsy results that were negative for CIN 2/3 were more frequent among patients with negative HPV testing (13/61 [21.3%]) than among those with positive HPV tests (58/418 [13.9%]; P=0.03). Additionally, among 59 patients diagnosed with cervical cancer, 9 (15.3%) tested negative for HPV.<bold>Conclusion: </bold>The HPV test was negative for 12% and 15% of patients diagnosed with biopsy-proven CIN 2/3 and cervical cancer, respectively. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PAPILLOMAVIRUS diseases
*CERVICAL cancer diagnosis
*CERVICAL intraepithelial neoplasia
*BIOPSY
*COLPOSCOPY
*PAPILLOMAVIRUS disease diagnosis
*ACADEMIC medical centers
*CERVIX uteri
*LONGITUDINAL method
*MEDICAL screening
*PAPILLOMAVIRUSES
*CONIZATION
*DISEASE complications
*DIAGNOSIS
CERVIX uteri tumors
Subjects
Details
- Language :
- English
- ISSN :
- 00207292
- Volume :
- 136
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- International Journal of Gynecology & Obstetrics
- Publication Type :
- Academic Journal
- Accession number :
- 120533514
- Full Text :
- https://doi.org/10.1002/ijgo.12030