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Planar-Chiral Secondary Ferrocenylphosphanes.
- Source :
-
European Journal of Inorganic Chemistry . Jan2017, Vol. 2017 Issue 2, p256-262. 7p. - Publication Year :
- 2017
-
Abstract
- An efficient way to obtain pure diastereomeric mixtures of C-chiral, P-chiral, planar-chiral ferrocenylphosphanes is demonstrated by ortho-lithiation of enantiomerically pure ( SC)- N, N-dimethyl-1-ferrocenylethylamine (Ugi's amine) and reaction with RPX2 [X = Cl, Br; R = tBu, 2,4,6-Me3C6H2 (Mes)]. Four secondary ferrocenylphosphanes [Fe(C5H5)(1-PHR-2-CHR′NMe2-C5H3)] [R′ = H, R = tBu ( 1); R′ = H, R = Mes ( 2); R′ = CH3, R = tBu ( 3); R′ = CH3, R = Mes ( 4)] were synthesised and characterised. Pure diastereomeric mixtures of 1 and 2, a mixture of the pure major diastereomers of 4, as well as diastereomerically pure 3 were obtained by column chromatography under a nitrogen atmosphere. The formation of amine-borane or phosphane-borane adducts was studied by 11B and 31P NMR spectroscopy. A theoretical study was performed to understand the tendency of 1- 4 toward borane adduct formation. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14341948
- Volume :
- 2017
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- European Journal of Inorganic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 120746908
- Full Text :
- https://doi.org/10.1002/ejic.201600935