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Enhanced human osteoblast cell functions by “net-like” nanostructured cell-substrate interface in orthopedic applications.
- Source :
-
Materials Letters . Feb2017, Vol. 189, p275-278. 4p. - Publication Year :
- 2017
-
Abstract
- In this study, a novel “net-like” nanostructured cell-substrate interface to enhance the human osteoblast cell's functions in orthopedic applications was proposed. This novel “net-like” nanostructured surface was fabricated on 316L stainless steel by using ultrasonic shot peening. The in vitro study indicated that this “net-like” nanostructured cell-substrate interface could significantly enhance the attachment, spreading and proliferation rate of the human osteoblast cells (Saos-2) compared with the as-received surface with coarse grains. The enhancement of cell functions could be attributed to the high density grain boundaries in the “net-like” nanostructured surface, which could promote protein adsorption when material comes in contact with biological environments. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0167577X
- Volume :
- 189
- Database :
- Academic Search Index
- Journal :
- Materials Letters
- Publication Type :
- Academic Journal
- Accession number :
- 120833530
- Full Text :
- https://doi.org/10.1016/j.matlet.2016.11.077