Clinical significance of TFR2 and EPOR expression in bone marrow cells in myelodysplastic syndromes.

Authors :: Di Savino, Augusta
Gaidano, Valentina
Palmieri, Antonietta
Crasto, Francesca
Volpengo, Alessandro
Lorenzatti, Roberta
Scaravaglio, Patrizia
Manello, Alessandro
Nicoli, Paolo
Gottardi, Enrico
Saglio, Giuseppe
Cilloni, Daniela
De Gobbi, Marco
Source :: British Journal of Haematology. Feb2017, Vol. 176 Issue 3, p491-495. 5p. 1 Chart, 1 Graph.
Publication Year :: 2017
Abstract: The article presents the research conducted by scientist Augusta Di Savino and others on the clinical significance of transferrin receptor 2 (TFR2) and erythropoietin receptor (EPOR) expression in bone marrow cells in patients with myelodysplastic syndromes. It mentions that TFR2alpha and TFR2beta expression was positively correlated with that of EPOR and patients with very low/low TFR2alpha or TFR2beta expression levels had a significantly worse overall survival.

Subjects :: *MYELODYSPLASTIC syndromes
*TRANSFERRIN receptors
*ERYTHROPOIETIN receptors
*BONE marrow cells
*REFRACTORY anemia

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