Back to Search
Start Over
In situ generation and reactions of p-(trifluoromethyl)benzyl electrophiles: an efficient access to p-(trifluoromethyl)benzyl compounds.
- Source :
-
Chemical Communications . 2/4/2017, Vol. 53 Issue 10, p1668-1671. 4p. - Publication Year :
- 2017
-
Abstract
- A new three-component reaction, namely condensation–anti-Michael addition–aromatization, enabling the construction of benzylic compounds is disclosed. This reaction can not only act as an alternative approach to regioselective Csp2–H trifluoromethylation of arenes through an “aromatic to be” strategy, but also provides a simple, convenient, step-economic, and practical strategy for the in situ generation of electrophilic p-(trifluoromethyl)benzyl species under extremely mild conditions. [ABSTRACT FROM AUTHOR]
- Subjects :
- *BENZYL compounds
*AROMATIC compounds
*ELECTROPHILES
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 53
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 121046741
- Full Text :
- https://doi.org/10.1039/c6cc09268c