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ARResT/Interrogate: an interactive immunoprofiler for IG/TR NGS data.

Authors :
Bystry, Vojtech
Reigl, Tomas
Krejci, Adam
Demko, Martin
Hanakova, Barbora
Grioni, Andrea
Knecht, Henrik
Schlitt, Max
Dreger, Peter
Sellner, Leopold
Herrmann, Dietrich
Pingeon, Marine
Boudjoghra, Myriam
Rijntjes, Jos
Pott, Christiane
Langerak, Anton W.
Groenen, Patricia J. T. A.
Davi, Frederic
Brüggemann, Monika
Darzentas, Nikos
Source :
Bioinformatics. 2/1/2017, Vol. 33 Issue 3, p435-437. 3p.
Publication Year :
2017

Abstract

Motivation: The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task. Results: We thus implemented ARResT/Interrogate, a web-based, interactive application. It can organize and filter large amounts of immunogenetic data by numerous criteria, calculate several relevant statistics, and present results in the form of multiple interconnected visualizations. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13674803
Volume :
33
Issue :
3
Database :
Academic Search Index
Journal :
Bioinformatics
Publication Type :
Academic Journal
Accession number :
121091160
Full Text :
https://doi.org/10.1093/bioinformatics/btw634