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X-ray Crystal Structure of a Metalled Double-Helix Generated by Infinite and Consecutive C*-AgI-C* (C*:N1-Hexylcytosine) Base Pairs through Argentophilic and Hydrogen Bond Interactions.
- Source :
-
Chemistry - A European Journal . 2/10/2017, Vol. 23 Issue 9, p2103-2108. 6p. - Publication Year :
- 2017
-
Abstract
- The synthesis of a metalled double-helix containing exclusively silver-mediated C*−C* base pairs is reported herein (C*=N1hexylcytosine). Remarkably, it is the first crystal structure containing infinite and consecutive C*-AgI-C* base pairs that form a double helix. The AgI ion occupies the center between two C* residues with N(3)−Ag bond lengths of 2.1 Å and short AgI−AgI distances (3.1 Å) suggesting an interesting argentophilic attraction as a stabilization source of the helical disposition. The solid-state structure is further stabilized by metal-mediated base-pairs, hydrogen bonding and π-stacking interactions. Moreover, the angle N(3)−Ag-N(3) is almost linear in the [Ag(N1hexylcytosine)2]+ motif and the bases are not coplanar, thus generating a double-strand helical aggregate in the solid state. The noncovalent and argentophilic interactions have been rationalized based on DFT calculations. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09476539
- Volume :
- 23
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Chemistry - A European Journal
- Publication Type :
- Academic Journal
- Accession number :
- 121236487
- Full Text :
- https://doi.org/10.1002/chem.201604331