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X-Linked Retinoschisis in Juveniles: Follow-Up by Optical Coherence Tomography.
- Source :
-
BioMed Research International . 2/14/2017, Vol. 2017, p1-5. 5p. - Publication Year :
- 2017
-
Abstract
- Purpose. To explore the structural progression of X-linked retinoschisis (XLRS) in patients by using spectral-domain optical coherence tomography (SD-OCT). Design. Retrospective, observational study. Methods. Patients who were diagnosed with XLRS by genetic testing underwent comprehensive ophthalmological examinations from December 2014 to October 2016. Each eye was measured by SD-OCT using the same clinical protocol. A correlation between best-corrected visual acuity (VA) and SD-OCT measurements was observed. Results. Six patients demonstrated retinoschisis (12 eyes) and typical foveal cyst-like cavities (10 eyes) on SD-OCT images with a mean logMAR VA of 0.48. The median age was 7.5 years at the initial visit. Their foveal retinal thickness (516.9 μm) and choroid thickness (351.4 μm) decreased at a rate of 38.1 and 7.5 μm, respectively, at the 10.5-month follow-up visit; however, there were no significant differences (P=0.622 and P=0.406, resp.). There was no significant correlation between VA, the foveal retinal thickness, and subfoveal choroid thickness. Conclusions. SD-OCT images for XLRS patients during the juvenile period revealed no significant changes in the fundus structure, including the foveal retinal thickness and choroid thickness within one-year follow-up. There was a lack of correlation between VA, foveal retinal thickness, and subfoveal choroid thickness. [ABSTRACT FROM AUTHOR]
- Subjects :
- *STATISTICAL correlation
*LONGITUDINAL method
*SCIENTIFIC observation
*PEDIATRICS
*PROBABILITY theory
*RESEARCH funding
*RETINA
*RETINAL diseases
*T-test (Statistics)
*UVEA
*VISUAL acuity
*OPTICAL coherence tomography
*RETROSPECTIVE studies
*DISEASE progression
*DATA analysis software
*DESCRIPTIVE statistics
*GENETICS
Subjects
Details
- Language :
- English
- ISSN :
- 23146133
- Volume :
- 2017
- Database :
- Academic Search Index
- Journal :
- BioMed Research International
- Publication Type :
- Academic Journal
- Accession number :
- 121269733
- Full Text :
- https://doi.org/10.1155/2017/1704623