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The short and the long: non-coding RNAs and growth factors in cancer progression.
- Source :
-
Biochemical Society Transactions . Feb2017, Vol. 45 Issue 1, p51-64. 14p. - Publication Year :
- 2017
-
Abstract
- A relatively well-understood multistep process enables mutation-bearing cells to form primary tumours, which later use the circulation system to colonize new locations and form metastases. However, in which way the emerging abundance of different non-coding RNAs supports tumour progression is poorly understood. Here, we review new lines of evidence linking long and short types of non-coding RNAs to signalling pathways activated in the course of cancer progression by growth factors and by the tumour micro-environment. Resolving the new dimension of non-coding RNAs in oncogenesis will probably translate to earlier detection of cancer and improved therapeutic strategies. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03005127
- Volume :
- 45
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Biochemical Society Transactions
- Publication Type :
- Academic Journal
- Accession number :
- 121309076
- Full Text :
- https://doi.org/10.1042/BST20160131