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Effect of oxytocin pretreatment on cannabis outcomes in a brief motivational intervention.
- Source :
-
Psychiatry Research . Mar2017, Vol. 249, p318-320. 3p. - Publication Year :
- 2017
-
Abstract
- Motivational enhancement therapy (MET) is efficacious in reducing cannabis use, yet benefits are generally short-lived. Oxytocin is a hypothalamic neuropeptide that promotes prosocial behaviors and plays a role in drug-related neuroadaptations; as such, oxytocin may enhance the effect of MET on cannabis outcomes. Cannabis dependent adults were randomized to receive MET plus oxytocin ( n =8) or placebo ( n =8). Participants receiving oxytocin showed reductions in amount of cannabis used daily and number of sessions per day. Participants receiving placebo did not evidence significant reductions. Powered clinical trials of oxytocin-enhanced MET for cannabis use disorder are warranted. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01651781
- Volume :
- 249
- Database :
- Academic Search Index
- Journal :
- Psychiatry Research
- Publication Type :
- Academic Journal
- Accession number :
- 121376613
- Full Text :
- https://doi.org/10.1016/j.psychres.2017.01.027