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Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells.

Authors :
Jin Choi, Yong
Lin, Chao-Po
Risso, Davide
Chen, Sean
Aquinas Kim, Thomas
How Tan, Meng
Billy Li, Jin
Wu, Yalei
Chen, Caifu
Xuan, Zhenyu
Macfarlan, Todd
Peng, Weiqun
Lloyd, K. C. Kent
Yong Kim, Sang
Speed, Terence P.
He, Lin
Source :
Science. 2/10/2017, Vol. 355 Issue 6325, p596-596. 1p. 1 Diagram.
Publication Year :
2017

Abstract

A summary is presented of the article "Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells," published in the online version of the journal. Topics discussed include the generation of embryonic and extraembryonic lineages in teratomas and the role of protein-coding genes, noncoding RNAs, and endogenous retroviruses in stem cell development.

Details

Language :
English
ISSN :
00368075
Volume :
355
Issue :
6325
Database :
Academic Search Index
Journal :
Science
Publication Type :
Academic Journal
Accession number :
121384000
Full Text :
https://doi.org/10.1126/science.aag1927