Phosphatidylinositol hydrolysis and an increase in Ca[sup2+] concentration in the signal-transduction process triggered by murine FcϒRIII are not required for protein kinase C translocation.

Investigates the correlation between phosphatidylinositol hydrolysis and an increase in calcium concentration in the signal-transduction process triggered by murine FcγRIII. Functional efficiency of FcγRIII to stimulate inositol phosphate metabolism; Effect of the deletion of intracellular sequences of the tumor necrosis factor a.