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Simultaneous Voltammetric Determination of Paracetamol, Codeine and Caffeine on Diamond-like Carbon Porous Electrodes.
- Source :
-
Electroanalysis . Mar2017, Vol. 29 Issue 3, p907-916. 10p. - Publication Year :
- 2017
-
Abstract
- A porous electrode material combining the features of vertically aligned multi-walled carbon nanotubes (VAMWCNT) and diamond-like carbon films (DLC) have been developed for a highly sensitive electrochemical sensor. For working electrode preparation, DLC has been grown onto VAMWCNT, forming a porous, conductive and stable composite. The electrochemical performance of this DLC:VAMWCNT electrode has been investigated toward detection and analysis of three well-known molecules, namely paracetamol, codeine and caffeine. A ternary mixture of these analytes was simultaneously determined under optimum experimental conditions using square-wave voltammetry. Wide linear concentration ranges and the limits of detection of 3.34×10−7 mol L−1, 1.57×10−7 mol L−1 and 3.67×10−7 mol L−1 were obtained for paracetamol, codeine and caffeine, respectively. We conclude that the proposed voltammetric method and the DLC:VAMWCNT electrode comprise a reliable methodology for simultaneous determination of paracetamol, codeine and caffeine in biological matrix samples. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10400397
- Volume :
- 29
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Electroanalysis
- Publication Type :
- Academic Journal
- Accession number :
- 121699088
- Full Text :
- https://doi.org/10.1002/elan.201600665