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Antiviral Drug-Resistant Influenza B Viruses Carrying H134N Substitution in Neuraminidase, Laos, February 2016.
- Source :
-
Emerging Infectious Diseases . Apr2017, Vol. 23 Issue 4, p686-690. 5p. 2 Charts, 2 Graphs. - Publication Year :
- 2017
-
Abstract
- In February 2016, three influenza B/Victoria/2/87 lineage viruses exhibiting 4- to 158-fold reduced inhibition by neuraminidase inhibitors were detected in Laos. These viruses had an H134N substitution in the neuraminidase and replicated efficiently in vitro and in ferrets. Current antiviral drugs may be ineffective in controlling infections caused by viruses harboring this mutation. [ABSTRACT FROM AUTHOR]
- Subjects :
- *INFLUENZA B virus
*OSELTAMIVIR
*NEURAMINIDASE
*HISTIDINE
Subjects
Details
- Language :
- English
- ISSN :
- 10806040
- Volume :
- 23
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Emerging Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 121976099
- Full Text :
- https://doi.org/10.3201/eid2304.161876