Intracellular and extracellular processing of chromogranin A.

Discusses the intracellular and extracellular processing of chromogranin A (CGA), a family of acidic soluble proteins which exhibit widespread distribution in endocrine cells and neurons. Determination of proteolytic cleavage sites involved in CGA degradation; Occurrence of CGA processing in the extracellular space after release, generating new shorter fragments.