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RGDC Peptide-Induced Biomimetic Calcium Phosphate Coating Formed on AZ31 Magnesium Alloy.
- Source :
-
Materials (1996-1944) . Apr2017, Vol. 10 Issue 4, p358. 15p. 2 Black and White Photographs, 3 Diagrams, 4 Charts, 9 Graphs. - Publication Year :
- 2017
-
Abstract
- Magnesium alloys as biodegradable metal implants have received a lot of interest in biomedical applications. However, magnesium alloys have extremely high corrosion rates a in physiological environment, which have limited their application in the orthopedic field. In this study, calcium phosphate compounds (Ca-P) coating was prepared by arginine-glycine-aspartic acid-cysteine (RGDC) peptide-induced mineralization in 1.5 simulated body fluid (SBF) to improve the corrosion resistance and biocompatibility of the AZ31 magnesium alloys. The adhesion of Ca-P coating to the AZ31 substrates was evaluated by a scratch test. Corrosion resistance and cytocompatibility of the Ca-P coating were investigated. The results showed that the RGDC could effectively promote the nucleation and crystallization of the Ca-P coating and the Ca-P coating had poor adhesion to the AZ31 substrates. The corrosion resistance and biocompatibility of the biomimetic Ca-P coating Mg alloys were greatly improved compared with that of the uncoated sample. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 19961944
- Volume :
- 10
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Materials (1996-1944)
- Publication Type :
- Academic Journal
- Accession number :
- 122765467
- Full Text :
- https://doi.org/10.3390/ma10040358