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Interactions between mesenchymal stem cells and the immune system.
- Source :
-
Cellular & Molecular Life Sciences . Jul2017, Vol. 74 Issue 13, p2345-2360. 16p. 3 Diagrams, 2 Charts. - Publication Year :
- 2017
-
Abstract
- In addition to being multi-potent, mesenchymal stem cells (MSCs) possess immunomodulatory functions that have been investigated as potential treatments in various immune disorders. MSCs can robustly interact with cells of the innate and adaptive immune systems, either through direct cell-cell contact or through their secretome. In this review, we discuss current findings regarding the interplay between MSCs and different immune cell subsets. We also draw attention to the mechanisms involved. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 1420682X
- Volume :
- 74
- Issue :
- 13
- Database :
- Academic Search Index
- Journal :
- Cellular & Molecular Life Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 123609871
- Full Text :
- https://doi.org/10.1007/s00018-017-2473-5