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A Practical Two-Step Synthesis of 3-Alkyl-2,3-dihydro-1H-isoindolin-1-ones.

Authors :
Ruan, Yuan‐Ping
Chen, Ming‐De
He, Ming‐Zhu
Zhou, Xiang
Huang, Pei‐Qiang
Source :
Synthetic Communications. 2004, Vol. 34 Issue 5, p853-861. 9p. 1 Diagram, 1 Chart.
Publication Year :
2004

Abstract

A flexible approach to 3-alkyl-2,3-dihydro-1H-isoindolin-1-ones via the reductive-alkylation procedure is described. Present method is versatile in scope, allowing the easy introduction of various C-3 carbon-substituents by Grignard addition to phthalimide. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00397911
Volume :
34
Issue :
5
Database :
Academic Search Index
Journal :
Synthetic Communications
Publication Type :
Academic Journal
Accession number :
12362910
Full Text :
https://doi.org/10.1081/SCC-120028358