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Impact of single centre kidney paired donation transplantation to increase donor pool in India: a cohort study.
- Source :
-
Transplant International . Jul2017, Vol. 30 Issue 7, p679-688. 10p. - Publication Year :
- 2017
-
Abstract
- In a living donor kidney transplantation ( LDKT) dominated transplant programme, kidney paired donation ( KPD) may be a cost-effective and valid alternative strategy to increase LDKT in countries with limited resources where deceased donation kidney transplantation ( DDKT) is in the initial stages. Here, we report our experience of 300 single-centre KPD transplantations to increase LDKT in India. Between January 2000 and July 2016, 3616 LDKT and 561 DDKT were performed at our transplantation centre, 300 (8.3%) using KPD. The reasons for joining KPD among transplanted patients were ABO incompatibility ( n = 222), positive cross-match ( n = 59) and better matching ( n = 19). A total of 124 two-way ( n = 248), 14 three-way ( n = 42), one four-way ( n = 4) and one six-way exchange ( n = 6) yielded 300 KPD transplants. Death-censored graft and patient survival were 96% ( n = 288) and 83.3% ( n = 250), respectively. The mean serum creatinine was 1.3 mg/dl at a follow-up of 3 ± 3 years. We credit the success of our KPD programme to maintaining a registry of incompatible pairs, counselling on KPD, a high-volume LDKT programme and teamwork. KPD is legal, cost effective and rapidly growing for facilitating LDKT with incompatible donors. This study provides large-scale evidence for the expansion of single-centre LDKT via KPD when national programmes do not exist. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09340874
- Volume :
- 30
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Transplant International
- Publication Type :
- Academic Journal
- Accession number :
- 124150765
- Full Text :
- https://doi.org/10.1111/tri.12956