NADPH Oxidase Mediates Lipopolysaccharide-induced Neurotoxicity and Proinflammatory Gene Expression in Activated Microglia.

Authors :: Qin, Liya
Yuxin Liu, Liya
Tongguang Wang
Sung-Jen Wei
Block, Michelle L.
Wilson, Belinda
Bin Liu
Jau-Shyong Hong
Source :: Journal of Biological Chemistry. 1/9/2004, Vol. 279 Issue 2, p1415-1421. 7p. 12 Color Photographs, 10 Graphs.
Publication Year :: 2004
Abstract: Characterizes the role of NADPH oxidase in mediating lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia. Mensencephalic neuron-glia cultures; Dopaminergic neurons; Neuron-enriched cultures.

Subjects :: *OXIDASES
*ENDOTOXINS
*NEUROTOXICOLOGY
*GENE expression
*MICROGLIA
*NEURONS

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