Reply to “commentary on ‘effect of β-alanine and the solvent composition on the solubility of solvate of calcium d-pantothenate containing four molecules of methanol and one molecule of water (d-PC·4MeOH·1H2O)’”.

Those comments from Acree on “Effect of β -alanine and the solvent composition on the solubility of solvate of calcium d -pantothenate containing four molecules of methanol and one molecule of water ( d -PC·4MeOH·1H 2 O)” are very valuable and helpful for improving the quality of our paper. Here according to the comments, we make a deep analysis and discussion of our article again. Firstly, we need to make a restatement that S 0 and S actually represent the solubility with no impurity in the solution and the solubility in the solution containing impurity in our article, respectively. Secondly, the experimental solubility was reanalysed by the new Cohen equation suggested by Acree Jr, and the results show that the original Cohen equation could give the better agreement. Finally, the modified Solubility-Polarity equation was adopted to correlate the solubility in terms of the relative dielectric constant. [ABSTRACT FROM AUTHOR]