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Potentiating the immune response of MUC1-based antitumor vaccines using a peptide-based nanovector as a promising vaccine adjuvant.
- Source :
-
Chemical Communications . 9/4/2017, Vol. 53 Issue 68, p9486-9489. 4p. - Publication Year :
- 2017
-
Abstract
- We utilize the supramolecular self-assembling peptide of Nap-GDFDFDYDK to construct chemically programmed, self-assembling and self-adjuvant MUC1-based antitumor vaccines. The vaccines, with antigen and adjuvant conjugation through covalent bonds, elicited both humoral and cellular immune responses. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MOLECULAR self-assembly
*PEPTIDES
*ANTINEOPLASTIC agents
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 53
- Issue :
- 68
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 124770468
- Full Text :
- https://doi.org/10.1039/c7cc04386d