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Enantioselective Synthesis of Spiro[indolizidine-1,3'-oxindoles].
- Source :
-
Organic Letters . Aug2017, Vol. 19 Issue 15, p4050-4053. 4p. - Publication Year :
- 2017
-
Abstract
- A three-step procedure for the enantioselective synthesis of spiro[indolizidine-1,3'-oxindoles], consisting of a stereoselective cyclocondensation reaction between (S)-tryptophanol and a prochiral or racemic δ-oxoester, bromination of the resulting oxazolopiperidone lactam, and a final stereoselective spirocyclization, is reported. [ABSTRACT FROM AUTHOR]
- Subjects :
- *BROMINATION
*OXINDOLES
*RACEMIC mixtures
Subjects
Details
- Language :
- English
- ISSN :
- 15237060
- Volume :
- 19
- Issue :
- 15
- Database :
- Academic Search Index
- Journal :
- Organic Letters
- Publication Type :
- Academic Journal
- Accession number :
- 124904584
- Full Text :
- https://doi.org/10.1021/acs.orglett.7b01818