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Outcomes Following Melody Transcatheter Pulmonary Valve Implantation for Right Ventricular Outflow Tract Dysfunction in Repaired Congenital Heart Disease: First Reported Australian Single Centre Experience.
- Source :
-
Heart, Lung & Circulation . Oct2017, Vol. 26 Issue 10, p1085-1093. 9p. - Publication Year :
- 2017
-
Abstract
- <bold>Background: </bold>Transcatheter pulmonary valve implantation (TPVI) with the Melody® transcatheter pulmonary valve (TPV) has demonstrated good haemodynamic and clinical outcomes in the treatment of right ventricular outflow tract (RVOT) conduit dysfunction in patients with repaired congenital heart disease CHD. We present the first Australian single centre experience of patients treated with Melody TPV.<bold>Method: </bold>A prospective, observational registry was developed to monitor clinical and haemodynamic outcomes in patients with RVOT dysfunction treated with the Melody TPV (Medtronic Inc, Minneapolis, United States).<bold>Results: </bold>Seventeen patients underwent TPVI with Melody TPV at The Prince Charles Hospital between January 2009 and February 2016 with a median (range) age of 34 (R: 15-60). Fifteen (88%) were NYHA Class 2 dyspnoea and 11 (59%) had corrected Tetralogy of Fallot. Indication for TPVI was stenosis in eight (47%), regurgitation in two (12%) and mixed dysfunction in seven (41%). Device implantation was successful in all patients. Peak RVOT gradient was significantly reduced and there was no significant regurgitation post procedure. There was one (6%) major procedural adverse event and two (12%) major adverse events at last recorded follow-up. There were no patient deaths. Follow-up cardiac magnetic resonance imaging revealed a significant reduction in indexed right ventricular end diastolic volume.<bold>Conclusion: </bold>This study confirms the safety and effectiveness of TPVI with Melody TPV for RVOT dysfunction in repaired CHD. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CONGENITAL heart disease
*PULMONARY valve
*CHEMOEMBOLIZATION
*CARDIAC magnetic resonance imaging
*HEALTH outcome assessment
*SURGERY
*THERAPEUTICS
*CARDIAC catheterization
*COMPUTED tomography
*ECHOCARDIOGRAPHY
*PROSTHETIC heart valves
*HEART valve diseases
*HEMODYNAMICS
*LONGITUDINAL method
*TIME
*VENTRICULAR outflow obstruction
*DISEASE complications
*DIAGNOSIS
Subjects
Details
- Language :
- English
- ISSN :
- 14439506
- Volume :
- 26
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Heart, Lung & Circulation
- Publication Type :
- Academic Journal
- Accession number :
- 124936806
- Full Text :
- https://doi.org/10.1016/j.hlc.2016.12.004