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A review of high performance liquid chromatographic-mass spectrometric urinary methods for anticancer drug exposure of health care workers.
- Source :
-
Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences . Aug2017, Vol. 1060, p316-324. 9p. - Publication Year :
- 2017
-
Abstract
- This review describes published high performance liquid chromatography/mass spectrometry (HPLC–MS) methods for the determination of anticancer drugs in human urine as non-invasive tool for monitoring of health care worker exposure to antineoplastic and cytotoxic drugs. HPLC–MS is a sensitive and specific method for analysis of anticancer drugs and their metabolites in biological fluids. In this review, a tabular summary and overview of published HPLC–MS methods are presented, as well as future trends and limitations in this area of research. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15700232
- Volume :
- 1060
- Database :
- Academic Search Index
- Journal :
- Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 124953669
- Full Text :
- https://doi.org/10.1016/j.jchromb.2017.06.028