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The impact of an increased progesterone-to-follicle number ratio on live delivery rates in women with normal ovarian reserve.
- Source :
-
International Journal of Gynecology & Obstetrics . Oct2017, Vol. 139 Issue 1, p84-89. 6p. - Publication Year :
- 2017
-
Abstract
- <bold>Objective: </bold>To explore the relationship between progesterone-follicle number (P/F) ratio and live delivery rate in patients with normal ovarian reserve undergoing cleavage-stage embryo transfer with a long gonadotropin-releasing hormone agonist cycle.<bold>Methods: </bold>The present retrospective study included data from patients younger than 38 years with normal ovarian reserve who were undergoing in vitro fertilization/intracytoplasmic sperm injection and embryo transfer at Zhongnan Hospital, Wuhan University, China, between January 1, 2009 and December 31, 2015. Patients underwent cleavage-stage fresh embryo transfer with a long gonadotropin-releasing hormone agonist cycle, and associations between P/F ratios and fertility/pregnancy outcomes were analyzed.<bold>Results: </bold>Patients with a P/F ratio of 0.11 or above had higher serum progesterone levels (P<0.001) and lower serum estradiol levels (P<0.001) on the day of human chorionic gonadotropin administration in comparison with patients with lower P/F ratios; elevated P/F ratios were also associated with fewer follicles at least 14 mm in size (P<0.001) and lower live delivery rates (P<0.001). Multiple logistic regression confirmed that P/F ratio was an independent predictor of live delivery rate (P=0.001).<bold>Conclusion: </bold>A P/F ratio of at least 0.11 was associated with lower live delivery rates in women with normal ovarian reserve undergoing cleavage-stage embryo transfer with a long gonadotropin-releasing hormone agonist cycle. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PROGESTERONE
*OVARIAN reserve
*INTRACYTOPLASMIC sperm injection
*LUTEINIZING hormone releasing hormone receptors
*LOGISTIC regression analysis
*EMBRYO transfer
*PHYSIOLOGY
*CHORIONIC gonadotropins
*DELIVERY (Obstetrics)
*ESTRADIOL
*FERTILIZATION in vitro
*INFERTILITY
*LONGITUDINAL method
*EVALUATION of medical care
*INDUCED ovulation
*PREGNANCY
*RETROSPECTIVE studies
Subjects
Details
- Language :
- English
- ISSN :
- 00207292
- Volume :
- 139
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- International Journal of Gynecology & Obstetrics
- Publication Type :
- Academic Journal
- Accession number :
- 125070559
- Full Text :
- https://doi.org/10.1002/ijgo.12256