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Lanostane-type triterpenoids from the fruiting body of Ganoderma calidophilum.
- Source :
-
Phytochemistry . Nov2017, Vol. 143, p104-110. 7p. - Publication Year :
- 2017
-
Abstract
- To search for active anti-cancer constituents in the fruiting body of Ganoderma calidophilum , we have successfully isolated four previously undescribed spiro-lactone lanostane triterpenoids (spiroganocalitones A-D), two previously undescribed lanostanoids (ganodecalones A and B) together with twenty-three known ones. The structures of the six previously undescribed compounds were elucidated based on 1D, 2D-NMR, and HRMS analyses. Ganoderone A showed moderate cytotoxic activity against K562, BEL7402, and SGC790 cell lines with IC 50 values of 7.62, 6.28, and 3.55 μ M, respectively. [ABSTRACT FROM AUTHOR]
- Subjects :
- *TRITERPENOIDS
*GANODERMATACEAE
*LANOSTANOIDS
*LACTONES
*SILICA gel
Subjects
Details
- Language :
- English
- ISSN :
- 00319422
- Volume :
- 143
- Database :
- Academic Search Index
- Journal :
- Phytochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 125178153
- Full Text :
- https://doi.org/10.1016/j.phytochem.2017.07.015