Efficient Synthesis of N-Alkyl Polyhydroxylated Pipecolamide Compounds from D-Glucurono-6,3-lactone.

N-Alkyl pipecolamides were efficiently synthesized from D-glucurono-6,3-lactone via a key 5-azido N-alkylamide intermediate that can be used as a scaffold for the synthesis of 4-amino and N-sulfonated pipecolamide derivatives. [ABSTRACT FROM AUTHOR]