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ParaHydrogen Hyperpolarized Substrates for Molecular Imaging Studies.
- Source :
-
Israel Journal of Chemistry . Sep2017, Vol. 57 Issue 9, p833-842. 10p. - Publication Year :
- 2017
-
Abstract
- Parahydrogen induced polarization (PHIP) is a chemistry based, cheap and easy to handle hyperpolarization method that allows to increase the sensitivity of magnetic resonance signals of several orders of magnitude. This powerful tool has not coalesced in the field of biomedical studies due to the lack of suitable hyperpolarization substrates, of commercial parahydrogen polarizers and to the presence of metal complex in the solutions of products. Here is reported an overview of the recent advances in these fields, with particular attention to the issues that have been tackled in order to allow the translation of parahydrogen based hyperpolarization methods into a widely applicable molecular imaging tool for biomedical research. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00212148
- Volume :
- 57
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Israel Journal of Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 125370224
- Full Text :
- https://doi.org/10.1002/ijch.201700030