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Adult reference intervals for IgG subclasses with Siemens immunonephelometric assays in Chinese population.
- Source :
-
Allergy, Asthma & Clinical Immunology . 10/5/2017, Vol. 13, p1-4. 4p. - Publication Year :
- 2017
-
Abstract
- Objective: To determine the adult reference intervals for the Siemens IgG subclass reagents. Methods: 636 blood samples of healthy adults were analyzed to determine the level of IgG subclass using the reagents of Siemens immunonephelometric assay with molecular biology kits. Results: IgGSc reference intervals were as follows: IgG1 4.45-9.76 g/L, IgG2 2.07-8.57 g/L, IgG3 0.08-0.80 g/L and IgG4 0.05-1.54 g/L. There was an excellent correlation between the total IgG and the sum of the IgG subclasses. No significant gender and age differences were observed. Conclusions: Our data provide the missing reference intervals and enable the use of the nephelometric IgG subclass reagents in Chinese. The study can offer reference on clinic diagnose. [ABSTRACT FROM AUTHOR]
- Subjects :
- *IMMUNOGLOBULIN G
*BLOOD sampling
*MOLECULAR biology
*MYELOMA proteins
Subjects
Details
- Language :
- English
- ISSN :
- 17101484
- Volume :
- 13
- Database :
- Academic Search Index
- Journal :
- Allergy, Asthma & Clinical Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 125509939
- Full Text :
- https://doi.org/10.1186/s13223-017-0216-7