Syndrome de Gorlin-Goltz: du diagnostic au traitement: à propos d'une observation.

Gorlin syndrome, also known as nevoid basal cell carcinoma syndrome (NBCCS), is a hereditary condition transmitted as an autosmal dominant trait, due to a mutation in the tumor suppressor gene PTCH mapped to chromosome 9q 22.3-q31. It is a rare syndrome characterized by a series of developmental abnormalities and predisposition to various cancers. The Gorlin syndrome - Glotz combines several general clinical manifestations including many basal cell carcinomas and nevi, palmar-plantar hyperkeratosis, skeletal abnormalities, intracranial ectopic calcifications, facial dysmorphism with macrocephaly. The dentist have an important role in the diagnosis of this syndrome through maxillofacial signs specific to its expression including: keratocysts odontogenic, inclusions and dental ectopias that can be inaugural. [ABSTRACT FROM AUTHOR]