Back to Search Start Over

Future insights in fungal metabolic engineering.

Authors :
Wakai, Satoshi
Arazoe, Takayoshi
Ogino, Chiaki
Kondo, Akihiko
Source :
Bioresource Technology. Dec2017 Part B, Vol. 245, p1314-1326. 13p.
Publication Year :
2017

Abstract

Filamentous fungi exhibit versatile abilities, including organic acid fermentation, protein production, and secondary metabolism, amongst others, and thus have applications in the medical and food industries. Previous genomic analyses of several filamentous fungi revealed their further potential as host microorganisms for bioproduction. Recent advancements in molecular genetics, marker recycling, and genome editing could be used to alter transformation and metabolism, based on optimized design carbolated with computer science. In this review, we detail the current applications of filamentous fungi and describe modern molecular genetic tools that could be used to expand the role of these microorganisms in bioproduction. The present review shed light on the possibility of filamentous fungi as host microorganisms in the field of bioproduction in the future. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09608524
Volume :
245
Database :
Academic Search Index
Journal :
Bioresource Technology
Publication Type :
Academic Journal
Accession number :
125705237
Full Text :
https://doi.org/10.1016/j.biortech.2017.04.095