Free and total plasma concentrations of elvitegravir/cobicistat during pregnancy and postpartum: a case report.

The article presents a case study which focused on the pharmacokinetics of hepatic extraction drug elvitegravir (EVG) and its booster cobicistat (cobi) in a 37-year-old HIV-infected pregnant woman. Topics discussed include the medical history and previous antiretroviral treatments received by the patient, the use of liquid chromatography to quantify the patient's total EVG/cobi concentrations, and brief details about EVG metabolism during pregnancy.