连续负荷量新活素治疗难治性心力衰竭患者的临床疗效观察.

Objective: To investigate the clinical effects of continuous load volume new living factor on the refractory heart failure. Methods: 65 cases of patients with refractory heart failure patients were randomly divided into two groups. The contr ol group was given conventional treatment and Nitroglycerin Injection, and the observation group was given new living factor with conventional treatment. The curative effect, changes of pulmonary artery wedge pressure (PAWP). pulmonary artery pressure (PAP), serum anti hs-CRP. brain natriuretic peptide (BNP) levels before treatment and at 24. 36.48 h after treatment were compared between the two gr oups. Results: After treatment, the effective rate of observation group was 87.9%, which was higher than that of the control group (65.6%, P<0.05). The reduction value of PAWP and PAP levels of both groups were gradually increased at 24. 36. 48 h after treatment, which were significantly higher in the observation group than those of the control gr oup at the same time points(P<0.05). At 24. 36. 4S h after treatment, the serum hs-CRP and BNP levels were decreased with the extension of treatment time (P<0.05). which were significantly lower in the observation group than those of the control group at the same tune points (P<0.05). Conclusion: Based On the conventional treatment, continuous loading volume of new living factor can improve the therapeutic effect, and reduce cardiac preload. hs-CRP and BNP levels, improve the myocardial remodeling of patients with refractory heart failure. [ABSTRACT FROM AUTHOR]