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Risk Factors for Measles Virus Infection Among Adults During a Large Outbreak in Postelimination Era in Mongolia, 2015.

Authors :
Hagan, José E.
Yoshihiro Takashima
Sarankhuu, Amarzaya
Dashpagma, Otgonbayar
Jantsansengee, Baigalmaa
Pastore, Roberta
Nyamaa, Gunregjav
Yadamsuren, Buyanjargal
Mulders, Mick N.
Wannemuehler, Kathleen A.
Anderson, Raydel
Bankamp, Bettina
Rota, Paul
Goodson, James L.
Takashima, Yoshihiro
Source :
Journal of Infectious Diseases. 11/15/2017, Vol. 216 Issue 10, p1187-1195. 9p.
Publication Year :
2017

Abstract

<bold>Background: </bold>In 2015, a large nationwide measles outbreak occurred in Mongolia, with very high incidence in the capital city of Ulaanbaatar and among young adults.<bold>Methods: </bold>We conducted an outbreak investigation including a matched case-control study of risk factors for laboratory-confirmed measles among young adults living in Ulaanbaatar. Young adults with laboratory-confirmed measles, living in the capital city of Ulaanbaatar, were matched with 2-3 neighborhood controls. Conditional logistic regression was used to estimate adjusted matched odds ratios (aMORs) for risk factors, with 95% confidence intervals.<bold>Results: </bold>During March 1-September 30, 2015, 20 077 suspected measles cases were reported; 14 010 cases were confirmed. Independent risk factors for measles included being unvaccinated (adjusted matched odds ratio [aMOR] 2.0, P < .01), being a high school graduate without college education (aMOR 2.6, P < .01), remaining in Ulaanbaatar during the outbreak (aMOR 2.5, P < .01), exposure to an inpatient healthcare facility (aMOR 4.5 P < .01), and being born outside of Ulaanbaatar (aMOR 1.8, P = .02).<bold>Conclusions: </bold>This large, nationwide outbreak shortly after verification of elimination had high incidence among young adults, particularly those born outside the national capital. In addition, findings indicated that nosocomial transmission within health facilities helped amplify the outbreak. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00221899
Volume :
216
Issue :
10
Database :
Academic Search Index
Journal :
Journal of Infectious Diseases
Publication Type :
Academic Journal
Accession number :
126691466
Full Text :
https://doi.org/10.1093/infdis/jix449