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ALLERGIC CONTACT SENSITIZATION TO THE TOLUIC ACIDS.
- Source :
-
Journal of Investigative Dermatology . Nov73, Vol. 61 Issue 5, p282-285. 4p. - Publication Year :
- 1973
-
Abstract
- Para-toluic acid (1:4 methylbenzoic acid) and ortho-toluic acid were found to be potent allergic sensitizers when applied to human skin. Cross-sensitivity was found between all three isomers, p-toluic, m-toluic, and o-toluic acids. It is suggested that this cross-sensitivity is explicable in terms of carrier protein specificity rather than by the presence of a common chemical sequence in the hapten or by conversion of the cross-reactants to an identical hapten. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ALLERGIES
*PROTEINS
*HAPTENS
*ANTIGENS
*BIOMOLECULES
*ORGANIC compounds
Subjects
Details
- Language :
- English
- ISSN :
- 0022202X
- Volume :
- 61
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Journal of Investigative Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 12676503
- Full Text :
- https://doi.org/10.1111/1523-1747.ep12676503