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Multiple Variable First Exons: A Mechanism for Cell- and Tissue-Specific Gene Regulation.
- Source :
-
Genome Research . Jan2004, Vol. 14 Issue 1, p79-89. 11p. 1 Black and White Photograph, 5 Diagrams. - Publication Year :
- 2004
-
Abstract
- Focuses on the family of neural protocadherin (Pcdh) proteins encoded by closely linked mammalian gene clusters. Determination of the cell-specific expression of each Pcdh gene; Implication for combining variable-exon promoter activation and cis-splicing of the corresponding variable exon to the first constant exon; Association of genomic organization with genetic mechanism for directing distinct cell- and tissue-specific patterns of gene expression.
Details
- Language :
- English
- ISSN :
- 10889051
- Volume :
- 14
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Genome Research
- Publication Type :
- Academic Journal
- Accession number :
- 12690135
- Full Text :
- https://doi.org/10.1101/gr.1225204