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Uveitic Glaucoma: Long-term Clinical Outcome and Risk Factors for Progression.
- Source :
-
Ocular Immunology & Inflammation . Dec2017, Vol. 25 Issue 6, p740-747. 8p. - Publication Year :
- 2017
-
Abstract
- <bold>Purpose: </bold>To study the long-term clinical outcomes of uveitic glaucoma and to identify risk factors for progression.<bold>Methods: </bold>Retrospective study of uveitic glaucoma patients in two tertiary medical centers in 2003-2015. Patient- and disease-related data was retrieved. Clinical parameters and visual fields measured at predetermined time points were recorded. Outcome measures included maintaining intraocular pressure ≤21 mmHg and preserving visual fields.<bold>Results: </bold>Included were 34 patients (53 eyes), with a mean follow-up of 7 years. Idiopathic anterior uveitis and open-angle glaucoma were most common. In total, 62% of eyes were steroid responders. Higher IOP was associated with posterior synechiae, peripheral-anterior synechiae, steroidal, and immunomodulatory therapy (p<0.05). Glaucomatous field defects developed in 49%, with most showing no progression, despite elevation of cup-to-disc ratio (p<0.05).<bold>Conclusions: </bold>Chronic severe uveitis, expressed by structural complications and immunomodulatory therapy, was associated with high IOP and the need for more IOP lowering medications, but was unrelated to glaucomatous damage. [ABSTRACT FROM AUTHOR]
- Subjects :
- *GLAUCOMA
*UVEITIS
*INTRAOCULAR pressure
*IMMUNOREGULATION
*HEALTH outcome assessment
*DISEASE progression
*DISEASE risk factors
*GLAUCOMA diagnosis
*COMPARATIVE studies
*LONGITUDINAL method
*RESEARCH methodology
*MEDICAL cooperation
*RESEARCH
*VISUAL acuity
*VISUAL fields
*EVALUATION research
*TREATMENT effectiveness
*RETROSPECTIVE studies
*OCULAR hypertension
*DISEASE complications
*DIAGNOSIS
THERAPEUTIC use of glucocorticoids
Subjects
Details
- Language :
- English
- ISSN :
- 09273948
- Volume :
- 25
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Ocular Immunology & Inflammation
- Publication Type :
- Academic Journal
- Accession number :
- 126917805
- Full Text :
- https://doi.org/10.1080/09273948.2016.1255341