Back to Search
Start Over
Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable.
- Source :
-
Chemosphere . Mar2018, Vol. 194, p147-157. 11p. - Publication Year :
- 2018
-
Abstract
- Numerous epidemiological studies suggest that air pollutants cause a decline in the quality of human spermatozoa and thus a reduction in fertility. However, the exact cause of infertility remains unknown. Air pollution gases, such as NH 3 and H 2 S are either free or bound to airborne particular materials (PM) and are abundant and reactive. The aim of this current investigation was to explore the impacts of NH 3 and/or H 2 S on male fertility and the underlying mechanisms. Male mouse exposed to H 2 S and/or NH 3 and after two generations were used to evaluate the impacts on fertility. The fertility, and spermatozoa quality parameters and proteins involved in spermatogenesis were investigated. Our current investigation demonstrates: i) H 2 S and/or NH 3 decrease male fertility by 20–30%, reduce the spermatozoa concentration about 20–40%, decrease 10–20%, increase around 30%; ii) the reduction in male fertility by H 2 S and/or NH 3 can be inheritable; iii) H 2 S and/or NH 3 can diminish male fertility through the disruption of spermatogenesis without affecting other body parameters such as body weight and organ index. One component of air pollutants, for example NH 3 , does not have a severe impact; however, two or more pollutants such as H 2 S and NH 3 combined can cause serious health problems, especially with regard to male fertility. We suggest that greater attention should be paid to these air pollutants to improve human health and fertility. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00456535
- Volume :
- 194
- Database :
- Academic Search Index
- Journal :
- Chemosphere
- Publication Type :
- Academic Journal
- Accession number :
- 126946911
- Full Text :
- https://doi.org/10.1016/j.chemosphere.2017.11.164