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Maternal and Neonatal Outcomes of Induction of Labor Compared with Planned Cesarean Delivery in Women with Preeclampsia at 34 Weeks' Gestation or Longer.

Authors :
Kawakita, Tetsuya
Bowers, Katherine
Source :
American Journal of Perinatology. 2018, Vol. 35 Issue 1, p95-102. 8p.
Publication Year :
2018

Abstract

Objective This study aims to compare outcomes of induction with planned cesarean in women with preeclampsia. Study Design A retrospective cohort study, including women with singleton pregnancies, preeclampsia (mild, severe, and superimposed), and without previous cesarean at 34 weeks' gestation was conducted. Outcomes included primary outcome (intensive care unit [ICU] admission, thromboembolism, transfusion, and hysterectomy), composite severe neonatal outcome (asphyxia, arterial cord pH < 7.0, hypoxic-ischemic encephalopathy, and 5-minute Apgar score < 5), neonatal ICU (NICU) admission, transient tachypnea of newborn (TTN), and respiratory distress syndrome (RDS). Adjusted odds ratios (aORs) with 95% confidence intervals (CIs) were calculated, controlling for confounders. Results Of 5,506 women with preeclampsia at 34 weeks' gestation, 5,104 (92.7%) women underwent induction. Induction compared with planned cesarean was not associated with an increased risk of the primary outcome but was related to increased risks of ICU admission (aOR: 3.29; 95% CI: 1.02-10.64), and linked to decreased risks of composite neonatal outcome (aOR: 0.32; 95% CI: 0.10-0.99), NICU admission (aOR: 0.60; 95% CI: 0.43-0.84), TTN (aOR: 0.38; 95% CI: 0.22-0.64), and RDS (aOR: 0.44; 95% CI: 0.22-0.86). Conclusion Induction was not associated with an increased risk of the primary outcome but was associated with an increased risk of ICU admission and decreased risks of neonatal outcomes. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
07351631
Volume :
35
Issue :
1
Database :
Academic Search Index
Journal :
American Journal of Perinatology
Publication Type :
Academic Journal
Accession number :
126955531
Full Text :
https://doi.org/10.1055/s-0037-1606185