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Three-Dimensional Barcodes with Ultrahigh Encoding Capacities: A Flexible, Accurate, and Reproducible Encoding Strategy for Suspension Arrays.
- Source :
-
Chemistry of Materials . 12/26/2017, Vol. 29 Issue 24, p10398-10408. 11p. - Publication Year :
- 2017
-
Abstract
- Novel 3D barcodes with an extraordinarily high encoding capacity are developed through a flexible, accurate, and reproducible method. Here, the three dimensions refer to the size, fluorescence emission wavelength, and intensity of the barcodes. As a proof of concept, a 3D barcode library with an encoding capacity of 100 flow cytometry-distinguishable barcodes is achieved successfully by combining the multiscaled host particles with a set of guest nanoparticles owning to their individual different fluorescent intensity via an ingenious host-guest structure, where fluorescein isothiocyanate and a kind of quantum dots are separately loaded inside. Five-plexed tumor marker detection is further implemented, and the results demonstrate the strong feasibility of 3D barcodes in multiplex assays. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 08974756
- Volume :
- 29
- Issue :
- 24
- Database :
- Academic Search Index
- Journal :
- Chemistry of Materials
- Publication Type :
- Academic Journal
- Accession number :
- 126974353
- Full Text :
- https://doi.org/10.1021/acs.chemmater.7b03811