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Stability and Hopf bifurcation of a delayed viral infection model with logistic growth and saturated immune impairment.

Authors :
Jianwen Jia
Jie Li
Source :
Mathematical Methods in the Applied Sciences. 1/30/2018, Vol. 41 Issue 2, p839-849. 11p.
Publication Year :
2018

Abstract

In this paper, the stability and Hopf bifurcation of a delayed viral infection model with logistic growth and saturated immune impairment is studied. It is shown that there exist 3 equilibria. The sufficient conditions for local asymptotic stability of the infection-free equilibrium and no-immune equilibrium are given. We also discussed the local stability of positive equilibrium and the existence of Hopf bifurcation. Moreover, the direction and stability of Hopf bifurcation is obtained by using standard form theory and the center manifold theorem. Finally, numerical simulations are performed to verify the theoretical conclusions. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01704214
Volume :
41
Issue :
2
Database :
Academic Search Index
Journal :
Mathematical Methods in the Applied Sciences
Publication Type :
Academic Journal
Accession number :
127010783
Full Text :
https://doi.org/10.1002/mma.4648