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The synthesis of 6,6-difluoroshikimic acid
- Source :
-
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry . Apr2004, Vol. 45 Issue 17, p3429. 4p. - Publication Year :
- 2004
-
Abstract
- The synthesis of 6,6-difluoroshikimic acid (4) has been achieved in nine steps from the enantiopure diol 9, which is derived from microbial dihydroxylation of iodobenzene. The synthetic strategy has also been demonstrated to be applicable to the preparation of other 6-substituted analogues of shikimic acid. [Copyright &y& Elsevier]
- Subjects :
- *IODOBENZENE
*SHIKIMIC acid
*HYDROXYLATION
*CARBOXYLIC acids
Subjects
Details
- Language :
- English
- ISSN :
- 00404039
- Volume :
- 45
- Issue :
- 17
- Database :
- Academic Search Index
- Journal :
- Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 12739566
- Full Text :
- https://doi.org/10.1016/j.tetlet.2004.03.033