The synthesis of 6,6-difluoroshikimic acid

Authors :: Humphreys, Jane L.
Lowes, David J.
Wesson, Karen A.
Whitehead, Roger C.
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Apr2004, Vol. 45 Issue 17, p3429. 4p.
Publication Year :: 2004
Abstract: The synthesis of 6,6-difluoroshikimic acid (4) has been achieved in nine steps from the enantiopure diol 9, which is derived from microbial dihydroxylation of iodobenzene. The synthetic strategy has also been demonstrated to be applicable to the preparation of other 6-substituted analogues of shikimic acid. [Copyright &y& Elsevier]

Language :: English
ISSN :: 00404039
Volume :: 45
Issue :: 17
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 12739566
Full Text :: https://doi.org/10.1016/j.tetlet.2004.03.033