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PHYSIOLOGY OF ASTROGLIA.

Authors :
Verkhratsky, Alexei
Nedergaard, Maiken
Source :
Physiological Reviews. Jan2018, Vol. 98 Issue 1, p239-389. 151p.
Publication Year :
2018

Abstract

Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in morphological appearance; they express a multitude of receptors, channels, and membrane transporters. This complement underlies their remarkable adaptive plasticity that defines the functional maintenance of the CNS in development and aging. Astrocytes are tightly integrated into neural networks and act within the context of neural tissue; astrocytes control homeostasis of the CNS at all levels of organization from molecular to the whole organ. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00319333
Volume :
98
Issue :
1
Database :
Academic Search Index
Journal :
Physiological Reviews
Publication Type :
Academic Journal
Accession number :
127416690
Full Text :
https://doi.org/10.1152/physrev.00042.2016